“Joe has been working in brain research for decades and is a true pioneer in NMDA receptor pharmacology,” said
Dr. Moskal is a professor of biomedical engineering at
“It is difficult to describe the immense satisfaction I have in the incredible arc of the work I started many years ago, which began as a series of experiments to interrogate learning and memory processes and, ultimately, resulted in the discovery of numerous novel compounds now being studied in people who desperately need better treatment options,” said Dr. Moskal. “I take great pride in being involved in the discovery of these molecules, the research into their unique mechanism of action on NMDA receptors, and the unambiguous proof of their activity in the brain and CNS. Their advancement now relies most heavily on clinical development and I have the utmost confidence in the team of drug developers that is fiercely dedicated to translating that activity to efficacy and bringing these compounds to patients in need. I am very excited to be able to spend more time back in academia, but I am also very much looking forward to remaining close to this science and technology in my ongoing role as a scientific advisor.”
Dr. Moskal’s retirement from
Aptinyx Inc. is a clinical-stage biopharmaceutical company focused on the discovery, development, and commercialization of proprietary synthetic small molecules for the treatment of brain and nervous system disorders. Aptinyx has a platform for discovery of novel compounds that work through a unique mechanism to modulate—rather than block or over-activate—NMDA receptors and enhance synaptic plasticity, the foundation of neural cell communication. The company has three product candidates in clinical development in central nervous system indications, including chronic pain, post-traumatic stress disorder, and cognitive impairment associated with Parkinson’s disease. Aptinyx is also advancing additional compounds from its proprietary discovery platform, which continues to generate a rich and diverse pipeline of small-molecule NMDA receptor modulators with the potential to treat an array of neurologic disorders. For more information, visit www.aptinyx.com.
Statements contained in this press release regarding matters that are not historical facts are “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995. Because such statements are subject to risks and uncertainties, actual results may differ materially from those expressed or implied by such forward-looking statements. Such statements include, but are not limited to, statements regarding the company’s business plans and objectives, therapeutic effects of the company’s product candidates, expectations regarding the design, implementation, timing, and success of its current and planned clinical studies, and expectations regarding its uses and sufficiency of capital. Risks that contribute to the uncertain nature of the forward-looking statements include: the success, cost, and timing of the company’s product candidate development activities and planned clinical studies; the company’s ability to execute on its strategy; positive results from a clinical study may not necessarily be predictive of the results of future or ongoing clinical studies; regulatory developments in
Source: Aptinyx Inc.